Ubiquinone (Complex I)

Function

NADH-ubiquinone oxidoreductase (Complex I, EC 1.6.5.3) catalyzes the reduction of lipid soluble coenzyme Q (ubiquinone,CoQ) by water soluble NADH2− ; it is the first step in mitochondrial respiratory system.


Chen X., Qi F., Dash R., Beard D. A. Kinetic and regulation of mammalian NADH-ubiquinone oxidoreductase (Complex I), Biophysics Journal, 99(5), 1426-1436, 2010.