Carriers and pores

Carrier-Mediated Transport through Biomembranes. Transport in Biological Media

In living cells, the uptake and extrusion of hydrophilic molecules are generally governed by specialized membrane proteins known as transporters or carriers. Unlike pores or channels, they undergo enzyme-like binding and conformational changes to promote energetically downhill transport of their specific molecules. Elucidation of the catalytic properties of carriers by a combination of experimental measurements of carrier fluxes and analysis of those data by kinetic models is a fundamental endeavor in this field.

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