Aconitase

Reactants and Reaction

Aconitase is the second step in the citric acid cycle and is located between citrate synthase and isocitrate dehydrogenase. The reference chemical reaction is

$$\text{CIT}^{3-}\rightleftharpoons\text{ICIT}^{3-}$$

where the abbreviations for the biochemical species are listed below. The biochemical reaction, involving biochemical reactants that are sums of species is

$$\text{CIT}\rightleftharpoons\text{ICIT}$$

Wu, F, Yang F, Vinnakota KC, and Beard DA. Computer modeling of mitochondrial TCA cycle, oxidative phosphorylation, metabolite transport, and electrophysiology. J Biol Chem, Vol. 282(34): 24525-37, 2007.

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